An observational study of pain severity, cannabis use, and benefit expenditures in work disability
Abstract Objective: This study pools two cohorts of workers in Ontario interviewed 18 months following a disabling work-related injury to…
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Analytical description of adolescent binge drinking patients
Abstract Background: Binge drinking is a widespread health compromising behavior among adolescents and young adults, leading to significant health problems,…
Pulmonary Hypertension Is Associated with Worse Outcomes in Patients Hospitalized for Sick Sinus Syndrome
Abstract Sick sinus syndrome (SSS) is a condition of the sinoatrial node that arises from a constellation of aberrant rhythms,…
Molecular pharmacology of the onco-TRP channel TRPV6
Abstract TRPV6, a representative of the vanilloid subfamily of TRP channels, serves as the principal calcium uptake channel in the…
The Effects of Malnutrition on Inpatient Outcomes in Patients With Gastroparesis: A Nationwide Analysis
Abstract Introduction Gastroparesis (GP) is a chronic debilitating gastric motility disorder defined as delayed emptying of the stomach content without…
Exploring potential anti-inflammatory effects of medicinal cannabis
Abstract Purpose: Inflammation is thought to play a key role in malignant disease and may play a significant part in…
Cell death induction and intracellular vesicle formation in human colorectal cancer cells treated with Δ9-Tetrahydrocannabinol
Abstract Background: Δ9-Tetrahydrocannabinol (Δ9-THC) is a principal psychoactive extract of Cannabis sativa and has been traditionally used as palliative medicine…
Predicting Maternal and Infant Tetrahydrocannabinol Exposure in Lactating Cannabis Users: A Physiologically Based Pharmacokinetic Modeling Approach
Abstract A knowledge gap exists in infant tetrahydrocannabinol (THC) data to guide breastfeeding recommendations for mothers who use cannabis. In…
Origin recognition complex subunit 1(ORC1) is a potential biomarker and therapeutic target in cancer
Abstract Background: The origin recognition complex 1 (ORC1) is a large subunit of the origin recognition complex and acts as…
In Vitro Antiproliferative Effect of Cannabis Extract PHEC-66 on Melanoma Cell Lines
Abstract Melanoma, an aggressive form of skin cancer, can be fatal if not diagnosed and treated early. Melanoma is widely…