Pan-cancer analysis suggests that LY6H is a potential biomarker of diagnosis, immunoinfiltration, and prognosis
Abstract LY6H, a member of the lymphocyte antigen-6(LY6) gene family, is located on human chromosomes 6, 8, 11 and 19.…
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Expanding the repertoire of Antibody Drug Conjugate (ADC) targets with improved tumor selectivity and range of potent payloads through in-silico analysis
Abstract Antibody-Drug Conjugates (ADCs) have emerged as a promising class of targeted cancer therapeutics. Further refinements are essential to unlock…
A comprehensive prognostic and immune infiltration analysis of UBA1 in pan‐cancer: A computational analysis and in vitro experiments
Abstract Ubiquitin like modifier activating enzyme 1 (UBA1) plays an important role in immune regulation and cellular function. However, the…
Assessing the Impact of Drought Stress on Hemp (Cannabis sativa L.) Fibers
Abstract Drought can significantly impact fiber crop cultivation due to the plants’ specific water requirements and their extended vegetative period.…
The Effect of Cannabidiol on Performance and Post-Load Recovery among Healthy and Physically Active Individuals: A Systematic Review
Abstract Athlete performance and post-load recovery can be considered one of the most important and actively discussed topics in professional…
Dose-dependent effects of oral cannabidiol and delta-9-tetrahydrocannabinol on serum anandamide and related N-acylethanolamines in healthy volunteers
Abstract Background: The mental health benefits of cannabidiol (CBD) are promising but can be inconsistent, in part due to challenges…
BertTCR: a Bert-based deep learning framework for predicting cancer-related immune status based on T cell receptor repertoire
Abstract The T cell receptor (TCR) repertoire is pivotal to the human immune system, and understanding its nuances can significantly…
UBR1 is a prognostic biomarker and therapeutic target associated with immune cell infiltration in gastric cancer
Abstract Background: Ubiquitination is a targeted protein modification process mediated by intracellular molecules. UBR1 encodes a protein that binds to…
FDA-approved cannabidiol [Epidiolex®] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and declined neurogenesis
Abstract Background: Chronic Gulf War Illness (GWI) is characterized by cognitive and mood impairments, as well as persistent neuroinflammation and…
A mixed method study exploring similarities and differences in general and social services-specific barriers to treatment-seeking among individuals with a problematic use of alcohol, cannabis, or gambling
Abstract Introduction: The treatment gap for addictive disorders is one of the largest in health care. Several studies have investigated…