Potential tumor-specific antigens and immune landscapes identification for mRNA vaccine in thyroid cancer
Abstract Background: Tumor mRNA vaccines have been identified as a promising technology for cancer therapy in multiple cancer types, while…
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Identification of a Novel Antiviral Lectin against SARS-CoV-2 Omicron Variant from Shiitake-Mushroom-Derived Vesicle-like Nanoparticles
Abstract Lectins are a class of carbohydrate-binding proteins that may have antiviral activity by binding to the glycans on the…
Harnessing Cannabis sativa Oil for Enhanced Skin Wound Healing: The Role of Reactive Oxygen Species Regulation
Abstract Cannabis sativa emerges as a noteworthy candidate for its medicinal potential, particularly in wound healing. This review article explores…
LOTUS: Protocol for a double-blind placebo controlled randomized trial of hemp-derived cannabidiol for the treatment of cannabis use disorder
Abstract Background: As cannabis legalization continues to spread across the United States, average Δ9-tetrahydrocannabinol concentrations in recreational products have significantly…
Hemp regulates the fitness of corn earworm (Lepidoptera, Noctuidae) and its tachinid (Diptera) parasitoids
Abstract Pest management on hemp is still in its infancy, and biological control options are limited. Helicoverpa zea (corn earworm)…
Effects of Cannabidiol (CBD) on Doxorubicin-Induced Anxiety and Depression-like Behaviors and mRNA Expression of Inflammatory Markers in Rats
Abstract Background: Post-treatment side effects of chemotherapy can include cognitive deficits commonly known as Chemo-brain. The treatment of patients with…
Bioinformatic-Experimental Screening Uncovers Multiple Targets for Increase of MHC-I Expression through Activating the Interferon Response in Breast Cancer
Abstract Expression of major histocompatibility complex I (MHC-I) on tumor cells is extremely important for the antitumor immune response for…
Novel Oncogenic Value of C10orf90 in Colon Cancer Identified as a Clinical Diagnostic and Prognostic Marker
Abstract C10orf90, a tumor suppressor, can inhibit the occurrence and development of tumors. Therefore, we investigated the gene function of…
A Systematic Review of Delta-9-Tetrahydrocannabinol (∆9-THC) in Astrocytic Markers
Abstract Background: Astrocytic reactivity in substance use disorders (SUDs) has been extensively studied, yet the molecular effect of delta-9-tetrahydrocannabinol (∆9-THC,…
Asymmetry in Atypical Parkinsonian Syndromes—A Review
Abstract Background/Objectives: Atypical parkinsonian syndromes (APSs) are a group of neurodegenerative disorders that differ from idiopathic Parkinson’s disease (IPD) in…