Functional Adaptation in the Brain Habenulo–Mesencephalic Pathway During Cannabinoid Withdrawal
Abstract The mesolimbic reward system originating from dopamine neurons in the ventral tegmental area (VTA) of the midbrain shows a…
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Boosting Acetylcholine Signaling by Cannabidiol in a Murine Model of Alzheimer’s Disease
Abstract Alzheimer’s disease (AD) is a challenging medical issue that requires efficacious treatment options to improve long-term quality of life.…
Cannabis use and cognitive biases in people with first-episode psychosis and their siblings
Abstract Background: Cannabis use and familial vulnerability to psychosis have been associated with social cognition deficits. This study examined the…
The impact of schizophrenia genetic load and heavy cannabis use on the risk of psychotic disorder in the EU-GEI case-control and UK Biobank studies
Abstract Background: The association between cannabis and psychosis is established, but the role of underlying genetics is unclear. We used…
Copper homeostasis and copper-induced cell death in tumor immunity: implications for therapeutic strategies in cancer immunotherapy
Abstract Copper is an important trace element for maintaining key biological functions such as cellular respiration, nerve conduction, and antioxidant…
The influence of inactivated entomopathogenic bacterium Bacillus thuringiensis on the immune responses of the Colorado potato beetle
Abstract Background: Invasion of microorganisms into the gut of insects triggers a cascade of immune reactions accompanied by increased synthesis…
Bioefficiency of microencapsulated hemp leaf phytonutrient-based extracts to enhance in vitro rumen fermentation and mitigate methane production
Abstract The objective was to assess the supplementation with microencapsulation of hemp leaf extract (mHLE) utilized as a rumen enhancer…
Enhancing insights in sexually transmitted infection mapping: Syphilis in Forsyth County, North Carolina, a case study
Abstract In 2008–2011 Forsyth County, North Carolina (NC) experienced a four-fold increase in syphilis rising to over 35 cases per…
Synthesis and In Vitro Antileishmanial Efficacy of Novel Ethylene Glycol Analogues of Benzothiadiazine‐1,1‐dioxide
Abstract Leishmaniasis is a vector‐borne, parasitic disease affecting millions of people and animals worldwide. Current therapeutic options have proven to…
Optimized guidelines for feminized seed production in high-THC Cannabis cultivars
Abstract With the partial legalization of high-THC Cannabis sativa across 23 states for recreational use and 38 states for medical…