Improved Therapeutic Efficacy of Doxorubicin Chemotherapy With Cannabidiol in 4T1 Mice Breast Cancer Model
Abstract Background: High dose chemotherapy is one of the therapeutic strategies for breast cancer and doxorubicin (DOX) as a chemotherapy…
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A computational analysis of the oncogenic and anti-tumor immunity role of P4HA3 in human cancers
Abstract Prolyl-4-hydroxylase subunit alpha3 (P4HA3) is a triple helical procollagen synthesis protein. The role of P4HA3 in cancer development is…
Changes in legal referrals to specialty substance use disorder treatment from 2015–2019
Abstract Background: The policy landscape around substance use has changed dramatically in the past decade, which may have affected the…
Reducing the harms of cannabis use in youth post-legalization: insights from Ontario youth, parents, and service providers
Abstract Background: Canada has one of the highest prevalence of cannabis use globally, particularly among young adults aged 20–24 (50%)…
Tumor-immune hybrid cells evade the immune response and potentiate colorectal cancer metastasis through CTLA4
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s10238-024-01515-9. Article type: Research Article Keywords: Circulating hybrid cells,…
Screening of the Nutritional Properties, Bioactive Components, and Antioxidant Properties in Legumes
Abstract This study provides an assessment of nutrients (protein, amino acid profiles, fiber, starch), phenolic content TPC, flavonoid content TFC,…
Structure–Tissue Exposure/Selectivity Relationship (STR) on Carbamates of Cannabidiol
Abstract The structure–tissue exposure/selectivity relationship (STR) aids in lead optimization to improve drug candidate selection and balance clinical dose, efficacy,…
Cannabidiol Treatment for Adult Patients with Drug‐Resistant Epilepsies: A Real‐World Study in a Tertiary Center
Abstract Background and purpose: Around 30% of patients with epilepsy show drug‐resistant epilepsy (DRE). While cannabidiol has demonstrated efficacy as…
Microbial communities and their role in enhancing hemp fiber quality through field retting
Abstract Abstract: The current development of industrial hemp “Cannabis Sativa L.” fibers for technical textiles and industrial applications requires high-quality…
Mediating Effect of Job Burnout on the Relationship Between Organisational Support and Quiet Quitting in Nurses
Abstract Aim: The main purpose of this study was to investigate the potential mediating role of job burnout in the…