A Humanized CB1R Yeast Biosensor Enables Facile Screening of Cannabinoid Compounds
Abstract Yeast expression of human G-protein-coupled receptors (GPCRs) can be used as a biosensor platform for the detection of pharmaceuticals.…
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Comprehensive Insight into Cutaneous Application of Hemp
Abstract Known for its natural bio-compounds and therapeutic properties, hemp is being utilized in the development of skin products. These…
Exploring Cannabinoids as Potential Inhibitors of SARS-CoV-2 Papain-like Protease: Insights from Computational Analysis and Molecular Dynamics Simulations
Abstract The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has triggered a global COVID-19 pandemic, challenging healthcare…
Re-evaluation of the cardioprotective effects of cannabinoids against ischemia-reperfusion injury according to the IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria
Abstract Ischemic heart disease, associated with high morbidity and mortality, represents a major challenge for the development of drug-based strategies…
Mild Disease Course of Experimental Autoimmune Encephalomyelitis without Pertussis Toxin: Brain Transcriptome Analysis Reveals Similar Signaling to Active Lesions in Multiple Sclerosis
Abstract Experimental autoimmune encephalomyelitis (EAE) is a powerful model to study multiple sclerosis (MS). One of the approaches for EAE…
Comparative restriction enzyme analysis of methylation (CREAM) reveals methylome variability within a clonal in vitro cannabis population
Abstract The primary focus of medicinal cannabis research is to ensure the stability of cannabis lines for consistent administration of…
Revolutionizing Phenolic Content Determination in Vegetable Oils: A Cutting-Edge Approach Using Smartphone-Based Image Analysis
Abstract This study addressed the need for a more accessible and efficient method of analyzing phenolic content in vegetable oils.…
New Polymeric Hydrogels with Cannabidiol and α-Terpineol as Potential Materials for Skin Regeneration—Synthesis and Physicochemical and Biological Characterization
Abstract Dermatology and cosmetology currently prioritize healthy, youthful-looking skin. As a result, research is being conducted worldwide to uncover natural…
Cannabis use in a Canadian long-term care facility: a case study
Abstract Background: Following the legalization of cannabis in Canada in 2018, people aged 65 + years reported a significant increase…
Unraveling substance abuse among Malawian street children: A qualitative exploration
Abstract This qualitative study adopts a phenomenological and symbolic interactionist approach to comprehensively explore substance abuse among street children in…