Signal integrator function of CXXC5 in Cancer
Abstract Graphical Abstract: Article type: Review Article Keywords: CXXC5, Cell signaling, Cancer, Targeting therapy Authors: Zihao An, Jiepu Wang, Chengzuo…
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Structural and functional analysis reveals the catalytic mechanism and substrate binding mode of the broad-spectrum endolysin Ply2741
Abstract The emergence of antibiotic-resistant bacteria has attracted interest in the field of endolysins. Here, we analyzed the diversity of…
Physicians’ and patients’ perceived risks of chronic pain medication and co-medications in Quebec, Canada: a cross-sectional study
Abstract Background: The risks associated with medications and co-medications for chronic pain (CP) can influence a physician’s choice of drugs…
Prevalence, risk and resilience factors of mental health conditions among female sex workers: a systematic review and meta-analysis
Abstract Introduction: Female sex workers are a vulnerable hard-to-reach group. Research in this field is scarce due to several issues,…
Role of Cannabis in the Management of Chronic Non-Cancer Pain: A Narrative Review
Abstract Chronic non-cancer pain, defined by the Center for Disease Control and Prevention (CDC) as lasting beyond three months, significantly…
Characterization of Clostridium perfringens Phage Endolysin PlyDolk21
Abstract Background: Clostridium perfringens is a significant cause of food poisoning. Broad-spectrum antibiotics, commonly used to control C. perfringens, are…
Metabolic regulation of myeloid-derived suppressor cells in tumor immune microenvironment: targets and therapeutic strategies
Abstract Cancer remains a major challenge to global public health, with rising incidence and high mortality rates. The tumor microenvironment…
Comprehensive Pan-Cancer Analysis of RAC1 Decoding the Impact on Cancer Prognosis and B cell immune Regulation
Abstract RAC1, a member of the Rho family GTPases, has been implicated in various cancers, yet its pan-cancer landscape and…
Beyond BMI: Exploring Adolescent Lifestyle and Health Behaviours in Transylvania, Romania
Abstract Background/Objectives: This study aimed to investigate the lifestyle and the behavioral factors that influence the nutritional status of adolescents…
Construction of an anaplastic thyroid cancer stratification signature to guide immune therapy selection and validation of the pivotal gene HLF through in vitro experiments
Abstract Introduction: While most thyroid cancer patients have a favorable prognosis, anaplastic thyroid carcinoma (ATC) remains a particularly aggressive form…