Detection of Fast Decliner of Diabetic Kidney Disease Using Chiral Amino Acid Profiling: A Pilot Study
Abstract Biomarkers for the prediction of diabetic kidney disease are still unsatisfactory. Although D‐amino acids have been shown to reflect…
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ITGA4 as a potential prognostic and immunotherapeutic biomarker in human cancer and its clinical significance in gastric cancer: an integrated analysis and validation
Abstract Background: Integrin Subunit Alpha 4 (ITGA4), a member of the integrin protein family, is involved in the progression of…
System Analysis Identifies MYBL2 As a Novel Oncogene Target for Metastatic Prostate Cancer
Abstract Bone metastasis significantly contributes to the unfavorable prognosis observed in patients with prostate cancer. MYB proto-oncogene like 2 (MYBL2)…
KLK7 Involvement in Thyroid Papillary Carcinoma Cell Migration and Invasion by EMT via MAPK/ERK Pathways
Abstract Purpose: KLK7, also known as Kallikrein 7, is a secreted enzyme classified as a serine protease. Earlier studies have…
Evaluation of Small-Molecule Candidates as Modulators of M-Type K+ Currents: Impacts on Current Amplitude, Gating, and Voltage-Dependent Hysteresis
Abstract The core subunits of the KV7.2, KV7.3, and KV7.5 channels, encoded by the KCNQ2, KCNQ3, and KCNQ5 genes, are…
Development of a novel chimeric lysin to combine parental phage lysin and cefquinome for preventing sow endometritis after artificial insemination
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s13567-025-01457-4. Article type: Research Article Keywords: Endometritis, chimeric lysin,…
Extraction, GC-MS analysis, cytotoxic, anti-inflammatory and anticancer potential of Cannabis sativa female flower; in vitro, in vivo and in silico
Abstract This work examines the anticancer activity, the anti-inflammatory nature, and the cytotoxicity of the ethanol extract obtained from the…
Effect of Hemp Seed Oil on Milk Performance, Blood Parameters, Milk Fatty Acid Profile, and Rumen Microbial Population in Milk-Producing Buffalo: Preliminary Study
Abstract Vegetable oils containing unsaturated fatty acids play an important role in improving milk quality and enhancing buffaloes’ overall health.…
A Survey on the Criteria Used to Judge (Fake) News in Italian Population
Abstract Introduction: Fake news detection falls within the field of deception detection and, consequently, can be problematic due to no…
Cannabinoid spoilage, metabolism and cannabidiol(CBD) conversion to Tetrahydrocannabinol(THC) mechanisms with energetic parameters
Abstract Chemical redox mechanisms and thermodynamic parameters of the Cannabinoids Δ9-Tetrahydrocannabinol (THC) and cannabidiol (CBD) were determined theoretically and using…