Marijuana Poisoning in Canines in the Aburrá Valley (Antioquia-Colombia), 2023-2024
Abstract Background and Aim: Marijuana poisoning in canines is still considered a taboo topic. Poisoning in pets is becoming increasingly…
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Pan-Cancer Upregulation of the FOXM1 Transcription Factor
Abstract Background: The human FOXM1 transcription factor controls cell cycle progression and genome stability, and it has been correlated to…
Pan-Cancer Analysis of KANK2: Clinical and Molecular Insights into Tumor Progression and Therapeutic Implications
Abstract Background: KANK2, a gene crucial for cell migration and movement, is implicated in neoplastic and non-neoplastic diseases. This study…
TBX3 shapes an immunosuppressive microenvironment and induces immunotherapy resistance
Abstract Background: Identifying biomarkers that predict immunotherapy efficacy and discovering new targets for combination therapies are critical elements for improving…
A Structural Effect of the Antioxidant Curcuminoids on the Aβ(1–42) Amyloid Peptide
Abstract Investigating amyloid–β (Aβ) peptides in solution is essential during the initial stages of developing lead compounds that can influence…
Sarcopenia and cachexia: molecular mechanisms and therapeutic interventions
Abstract Sarcopenia is defined as a muscle‐wasting syndrome that occurs with accelerated aging, while cachexia is a severe wasting syndrome…
Therapeutic Endoscopic Interventions in Choledocholithiasis: Efficacy of Endoscopic Retrograde Cholangiopancreatography
Abstract Introduction: Choledocholithiasis, a condition characterized by stones in the common bile duct (CBD), frequently results in obstructive jaundice and…
Effects of a Cannabinoid-Based Phytocomplex (Pain ReliefTM) on Chronic Pain in Osteoarthritic Dogs
Abstract Chronic pain is one of the most disabling conditions in dogs, as it affects various aspects of a dog’s…
Plant Secondary Metabolites as Modulators of Mitochondrial Health: An Overview of Their Anti-Oxidant, Anti-Apoptotic, and Mitophagic Mechanisms
Abstract Plant secondary metabolites (PSMs) are a diverse group of bioactive compounds, including flavonoids, polyphenols, saponins, and terpenoids, which have…
Hypothesized pharmacogenomic and medication influences on tetrahydrocannabinol and cannabidiol metabolism in a cohort of unselected oral cannabis users
Abstract Background: Differences in cannabinoid metabolism and patient responses can arise even with equivalent doses and formulations. Genetic polymorphisms in…