Comprehensive Cellular Senescence Evaluation to Aid Targeted Therapies
Abstract Drug resistance to a single agent is common in cancer-targeted therapies, and rational drug combinations are a promising approach…
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The Multifaceted Role of lncRNA GAS5: A Pan-Cancer Analysis of Its Diagnostic, Prognostic, and Therapeutic Potential
Abstract Introduction: Cancer is a significant global health problem characterized by increased incidence and large disparities in outcomes. There is…
Identification of SETD4 as an Onco‐Immunological Biomarker Encompassing the Tumor Microenvironment, Prognoses, and Therapeutic Responses in Various Human Cancers
Abstract Background: SET domain‐containing protein 4 (SETD4) is a histone methyltransferase that has been shown to modulate cell proliferation, differentiation,…
Lebanese Cannabis sativa L. extract protects from cisplatin-induced nephrotoxicity in mice by inhibiting podocytes apoptosis
Abstract Background: Cisplatin is an anti-cancer drug used to treat a plethora of solid tumors. However, it is associated with…
Virulence of Five Root-Knot Nematodes (Meloidogyne spp.) on Nine Industrial Hemp (Cannabis sativa L.) Varieties and Nematicidal Potential of Hemp Seed Extracts Against Meloidogyne javanica
Abstract The most common and damaging plant parasitic nematodes are root-knot nematodes (RNK). Although hemp has been clearly infected by…
Utilization of Cannabidiol in Post-Organ-Transplant Care
Abstract Cannabidiol (CBD) is one of the major phytochemical constituents of cannabis, Cannabis sativa, widely recognized for its therapeutic potential.…
Deep eutectic solvent enhances antibacterial activity of a modular lytic enzyme against Acinetobacter baumannii
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-80440-z. Article type: Research Article Keywords: Modular lytic enzyme,…
Assessing Facial Thermal Nociceptive Response in Female Dogs After Elective Ovariohysterectomy Anesthetized with Isoflurane and Treated with Cannabidiol and Meloxicam Analgesia
Abstract The precise assessment of pain remains a critical concern in ensuring the welfare of companion animals. Consequently, innovative technologies…
Signal integrator function of CXXC5 in Cancer
Abstract Graphical Abstract: Article type: Review Article Keywords: CXXC5, Cell signaling, Cancer, Targeting therapy Authors: Zihao An, Jiepu Wang, Chengzuo…
Structural and functional analysis reveals the catalytic mechanism and substrate binding mode of the broad-spectrum endolysin Ply2741
Abstract The emergence of antibiotic-resistant bacteria has attracted interest in the field of endolysins. Here, we analyzed the diversity of…