Inside a Metastatic Fracture: Molecular Bases and New Potential Therapeutic Targets
Abstract Introduction: Bone metastases and pathological fractures significantly impact the prognosis and quality of life in cancer patients. However, clinical…
Free
Cellulose Extraction from Soybean Hulls and Hemp Waste by Alkaline and Acidic Treatments: An In-Depth Investigation on the Effects of the Chemical Treatments on Biomass
Abstract The agri-food supply chain and other industries that convert agricultural raw materials into various consumer goods generate large quantities…
Specificity of Thermal Destruction of Nonwoven Mixture Systems Based on Bast and Viscose Fibers
Abstract The research investigates the thermal behavior of mixed systems based on natural and artificial cellulose fibers used as precursors…
Targeting c-MET Alterations in Cancer: A Review of Genetic Drivers and Therapeutic Implications
Abstract This review focuses on the role of the MET proto-oncogene in cancer and how alterations in this gene contribute…
In Vitro Immunomodulatory Effects of Equine Adipose Tissue-Derived Mesenchymal Stem Cells Primed with a Cannabidiol-Rich Extract
Abstract Cell-based therapy using mesenchymal stem cells (MSCs) shows promise for treating several diseases due to their anti-inflammatory and immunomodulatory…
In Silico Prioritization of STAT1 3′ UTR SNPs Identifies rs190542524 as a miRNA-Linked Variant with Potential Oncogenic Impact
Abstract Background: Single-nucleotide polymorphisms (SNPs) are associated with multiple disorders and various cancer types. In the context of cancer, alterations…
Dysregulation of Locus-Specific Repetitive Elements in TCGA Pan-Cancers
Abstract Background: Understanding the role of repetitive elements (REs) in cancer development is crucial for identifying novel biomarkers and therapeutic…
Comprehensive pan-cancer analysis identified SLC16A3 as a potential prognostic and diagnostic biomarker
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s12935-025-03791-1. Article type: Research Article Keywords: SLC16A3, Pan-cancer, Prognosis,…
Gene expression profiling, prognosis, and immune microenvironment of KLF4 in malignancies
Abstract Gene expression profiling plays a crucial role in understanding the role of Krüppel-like factor 4 (KLF4) in the prognosis…
A preliminary randomized trial of the safety, tolerability, and clinical effects of hemp-derived cannabidiol in alcohol use disorder
Abstract Introduction: Cannabidiol (CBD) has recently gained attention for its potential therapeutic effects in substance use disorders, including Alcohol Use…