Readable research linked to original sources
Articles
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
10 articles
Newest firstPrevious research on the influence of substance use on PrEP uptake and adherence among transgender women has either relied on cross-sectional analyses or on combined samples of cisgender men who have sex with men and a much smaller subsample of transgender women. To the best of our knowledge, no longitudinal study has examined the relationship of substance use and PrEP use/adherence among young transgender women a…
Open article record in new tab ↗HIV disproportionately affects key populations (MSM, transgender people, sex workers and psychoactive substance users), who face greater social vulnerability and limited healthcare access. This study aimed at analyzing sexual orientation and gender identity and their association with sexual practices, sexually transmitted infections and psychoactive substance use among PrEP users. Method: A cross-sectional study w…
Open article record in new tab ↗The current PrEP delivery models in Uganda do not fully address the socio-economic, cultural, and logistical challenges faced by female sex workers (FSW), resulting in low adherence, mistrust in the healthcare system, and missed opportunities for effective PrEP care, as reflected in national data. This study evaluated the feasibility and effectiveness of a discrete-choice PrEP delivery model to improve PrEP uptake…
BackgroundHuman Immunodeficiency Virus (HIV) remains a significant public health challenge in Kenya, with women of reproductive age (WRA) at an increased risk. Although pre-exposure prophylaxis (PrEP) was integrated into Kenyas HIV prevention program close to a decade ago, it is still underutilized among WRA outside the key populations at a high risk for HIV. Understanding PrEP awareness and acceptability is cruci…
Background HIV Pre-Exposure Pophylaxis (PrEP) is provided free of charge by the Brazilian national health system. Though effective in preventing HIV infection, little is known about its impact on the health-related Quality of Life (QoL) of users. Objective The present study aimed at assessing the impact of PrEP on the QoL of its users. Methods Prospective cohort study with 114 HIV-negative participants aged 18 yea…
Background Long-acting (LA) injectable preexposure prophylaxis (PrEP) and on-demand PrEP may improve overall PrEP uptake among men who have sex with men (MSM), but little is understood about the PrEP option preferences of MSM in practical scenarios where they may choose between various PrEP options. Objective This study aims to examine the preferences for starting various PrEP options among a US nationwide online…
BackgroundCisgender female sex workers (FSWs) in sub-Saharan Africa have a high risk of HIV acquisition, highlighting the need for innovative approaches to expand coverage of evidence-based HIV prevention methods, including oral pre-exposure prophylaxis (PrEP). Our study aimed to identify FSWs preferences for a PrEP delivery model with structured choices for delivery location, services offered, and adherence suppo…
Open article record in new tab ↗BackgroundHIV pre-exposure prophylaxis (PrEP) is key to HIV transmission elimination but implementation is challenging and under-researched. We undertook a process evaluation of the first two years of a national PrEP programme to explore barriers and facilitators to implementation and to develop recommendations to improve implementation, focussing on PrEP uptake and initiation. MethodsStage 1 involved semi-structu…
Paclitaxel is an essential drug in the chemotherapy of ovarian, non-small cell lung, breast, gastric, endometrial, and pancreatic cancers. However, it frequently causes peripheral neuropathy as a dose-limiting factor. Animal models of paclitaxel-induced peripheral neuropathy (PIPN) have been established. The mechanisms of PIPN development have been elucidated, and many drugs and agents have been proven to have neu…
BackgroundPre-exposure prophylaxis (PrEP) is a promising strategy to break the chain of transmission of novel coronavirus (2019-nCoV). AimsThis trial aimed to evaluate the safety and efficacy of PrEP with various doses of HCQ against a placebo among high-risk healthcare providers (HCPs). MethodsA phase II, randomized, placebo-controlled trial was conducted at a tertiary care hospital. A total of 228 HCPs were scre…
Open article record in new tab ↗