Biofilm properties in relation to treatment outcome in patients with first-time periprosthetic hip or knee joint infection☆

Abstract Background: Periprosthetic joint infections (PJI) are challenging complications following arthroplasty. Staphylococci are a frequent cause of PJI and known biofilm producers. Biofilm formation decreases antimicrobial susceptibility, thereby challenging favourable treatment outcomes. The aims of this study were to characterize the biofilm abilities and antimicrobial susceptibilities of staphylococci causing first-time PJI and correlate them to clinical outcome (infection resolution and recurrence). Methods: Reoperations for PJI of the hip or knee between 1st January 2012 to 30th June 2015 performed at