p62/SQSTM1 in cancer: phenomena, mechanisms, and regulation in DNA damage repair

Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s10555-025-10250-w. Article type: Review Article Keywords: P62/SQSTM1, Modular structures, Tumorigenesis, DDR Authors: Xiaojuan Yang, Xunjie Cao, Qing Zhu ⚬ Affiliations: https://ror.org/00x43yy22Liver Digital Transformation Research Laboratory, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center of Biotherapy, Chengdu, Sichuan 610041 People’s Republic of China; https://ror.org/007mrxy13grid.412901.f0000 0004 1770 1022Division of Abdominal Tumor Multimodality Treatment, Department of General Surgery, West China Hospital, Sichuan University,