The significance of isolated hyperbilirubinemia in detecting asymptomatic common bile duct stones in patients undergoing laparoscopic cholecystectomy

Abstract Aim: The aim of this study was to evaluate the role of isolated hyperbilirubinemia in the detection of choledocholithiasis. Methods: A retrospective cohort study focused on adult patients diagnosed with gallstone disease, and undergoing intra-operative cholangiogram for suspected choledocholithiasis. Those presenting with isolated hyperbilirubinemia were investigated for their risk of choledocholithiasis, and were compared with those with normal liver function tests. Results: Out of the total 1274 patients undergoing intra-operative cholangiogram in the study period, only 18 exhibited isolated