Long-term exposure to air pollution and the incidence of Parkinson’s disease: A nested case-control study

Abstract Background: Previous studies revealed that chronic exposure to air pollution can significantly increase the risk of the development of Parkinson’s disease (PD), but this relationship is inconclusive as large-scale prospective studies are limited and the results are inconsistent. Therefore, the purpose of this study was to ascertain the adverse health effects of air pollution exposure in a nationwide population using a longitudinal approach. Materials and methods: We conducted a nested case-control study using the National Health Insurance Research Dataset