Promising Prodiginins Biological Activities

Abstract Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities. The present review aims to compile and analyze the main physicochemical and biological properties and mechanisms of action of prodiginins for microbial disease treatment, particularly SARS‐CoV‐2 disease and opportunistic infections related to COVID‐19. The interaction of prodigiosin, as a model molecule, with cellular membranes,