Acute Psychosis in Withdrawal from Nicotine Vaping in a Young Man with Comorbid Diabetic Ketoacidosis and Cannabis Use

Abstract Electronic delivery of nicotine, also termed “vaping,” has a growing evidence base suggesting potential harm through both exposure and withdrawal effects. The current report presents the case of a young man with multiple medical comorbidities, including insulin-dependent diabetes mellitus on an insulin pump and presumed Gilbert’s disease, and chronic cannabis use who experienced acute agitation with hallucinations in the context of quitting his vape pen “cold turkey” or abruptly discontinuing use without a nicotine replacement. While undergoing hospitalization for