Prognostic and immunological significance of CD82 in cancers with focus on hepatocellular carcinoma: A bioinformatics approach

Abstract Despite significant successes, immunotherapy continues to face numerous challenges in practical applications. CD82 plays an important role in the tumor microenvironment (TME) across various cancers. However, the prognostic value of CD82 in immunotherapy and its role in the immune response remain unclear. The expression levels of CD82 in healthy human tissues were assessed using the human protein atlas (HPA) database tool. The association among CD82 expression levels, copy number variations (CNV), and methylation was explored using the gene set