METTL3-mediated m6A modification of TACSTD2 mRNA inhibits papillary thyroid cancer progression by activating the TNF signaling and blocking epithelial–mesenchymal transition

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-30448-w. Article type: Research Article Keywords: Papillary thyroid cancer, TACSTD2, m6A, METTL3, YTHDC2, Cancer, Cell biology, Molecular biology, Oncology Authors: Jianting Man, Zongyuan Zhang, Tianxing Cui, Tiefeng Shi Affiliations: https://ror.org/03s8txj32grid.412463.60000 0004 1762 6325The Fourth Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, 246 Xuefu Road, Nangang, Harbin, 150000 Heilongjiang China; https://ror.org/00g2rqs52grid.410578.f0000 0001 1114 4286School of Stomatology, Southwest Medical University, Luzhou, 646000 Sichuan China License: ©