Genomic Landscapes and Hallmarks of Mutant RAS in Human Cancers
Abstract The complex genomic landscape of RAS-mutant tumors is reflective of selection processes in a cancer lineage–specific and context-dependent manner, highlighting differential therapeutic vulnerabilities that can be clinically translated. Authors: Robert B. Scharpf ⚬, Archana Balan ⚬, Biagio Ricciuti ⚬, Jacob Fiksel ⚬, Christopher Cherry ⚬, Chenguang Wang ⚬, Michele L. Lenoue-Newton ⚬, Hira A. Rizvi ⚬, James R. White ⚬, Alexander S. Baras ⚬, Jordan Anaya ⚬, Blair V. Landon ⚬, Marta Majcherska-Agrawal ⚬, Paola Ghanem ⚬, Jocelyn Lee
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