Antisense RNAs Influence Promoter Usage of Their Counterpart Sense Genes in Cancer

Abstract This study characterizes a previously unexplored role of ncNATs in regulation of isoform expression of associated sense genes, highlighting a mechanism of alternative promoter usage in cancer. Authors: Fernando Bellido Molias, Andre Sim, Ka Wai Leong, Omer An ⚬, Yangyang Song, Vanessa Hui En Ng, Max Wei Jie Lim, Chen Ying, Jasmin Xin Jia Teo, Jonathan Göke, Leilei Chen Affiliations: Cancer Science Institute of Singapore, National University of Singapore, Singapore.; Computational and Systems Biology, Genome Institute of Singapore, Singapore.;