Comprehensive Pan-Cancer Analysis of the Prognostic Role of KLF Transcription Factor 2 (KLF2) in Human Tumors

Abstract Background: KLF2 is a transcription factor expressed early in mammalian development that plays a role in many processes of development and disease. Recently, increasing studies revealed that KLF2 plays a key role in the occurrence and progression of cancer. Purpose: The aim of this study was to explore the role of KLF2 in various tumor types using the Cancer Genome Atlas dataset. Methods: Here, we set out to explore the role of KLF2 in 33 tumor types using TCGA