Multidimensional pan-cancer analysis reveals the impact of PPIA on tumor epigenetic modifications and immune regulation

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-05997-9. Article type: Research Article Keywords: Peptidyl-prolyl cis-trans isomerase A (PPIA), Pan-cancer, Bioinformatics, Biomarker, Data mining, Gene regulatory networks, Tumour biomarkers Authors: Yuanqian Yao ⚬, Xueqing Gong ⚬, Hui Li ⚬ Affiliations: https://ror.org/00pcrz470grid.411304.30000 0001 0376 205XHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610072 China; https://ror.org/00pcrz470grid.411304.30000 0001 0376 205XClinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075 China License: © The Author(s) 2025 CC BY-NC-ND 4.0