In Vitro Antiplasmodial Activity and Chemical Composition of Combretum aculeatum, a Medicinal Plant From Niger

Abstract Malaria remains a significant public health challenge in Niger, accounting for 5.6% of global malaria‐related deaths. Local medicinal plants are frequently used as traditional treatments for malaria, although their efficacy and safety are often insufficiently investigated. This study aims to evaluate the antiplasmodial activity and chemical composition of eight medicinal plants from Niger. Plant extracts were tested in vitro for their ability to inhibit the uptake of [3H]‐hypoxanthine in the Plasmodium falciparum NF54 chloroquine‐sensitive strain. The most active extract