Cannabis Use and Anxiety: Is Stress the Missing Piece of the Puzzle?
Abstract Objective: Comorbidity between anxiety and cannabis use is common yet the nature of the association between these conditions is…
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Coverage of overdose prevention programs for opiate users and injectors: a cross-sectional study
Abstract Background: The use of opiates, particularly heroin, remains an important cause of morbidity and mortality. Half of the deaths…
The Cannabis Pathway to Non-Affective Psychosis may Reflect Less Neurobiological Vulnerability
Abstract There is a high prevalence of cannabis use reported in non-affective psychosis. Early prospective longitudinal studies conclude that cannabis…
Long-term consequences of adolescent cannabinoid exposure in adult psychopathology
Abstract Marijuana is the most widely used illicit drug among adolescents and young adults. Unique cognitive, emotional, and social changes…
Addiction and reward-related genes show altered expression in the postpartum nucleus accumbens
Abstract Motherhood involves a switch in natural rewards, whereby offspring become highly rewarding. Nucleus accumbens (NAC) is a key CNS…
Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review
Keywords: PPAR gamma, Nuclear receptor, Natural product, Nutrition, Diabetes, 9-(, AF-2, activation function-2, CAP, c-Cbl-associated protein, Cdk5, cyclin-dependent kinase 5,…
Endocannabinoid 2-Arachidonoylglycerol Self-Administration by Sprague-Dawley Rats and Stimulation of in vivo Dopamine Transmission in the Nucleus Accumbens Shell
Abstract 2-Arachidonoylglycerol (2-AG) is the most potent endogenous ligand of brain cannabinoid CB1 receptors and is synthesized on demand from…
A protocol for the delivery of cannabidiol (CBD) and combined CBD and ∆9-tetrahydrocannabinol (THC) by vaporisation
Abstract Background: Significant interest has emerged in the therapeutic and interactive effects of different cannabinoids. Cannabidiol (CBD) has been shown…
Legalizing Cannabis: A physician’s primer on the pulmonary effects of marijuana
Abstract Habitual smoking of marijuana is associated with multiple respiratory symptoms such as cough, sputum production, and wheezing .These symptoms…
Prevalence and factors determining psychoactive substance (PAS) use among Hawassa University (HU) undergraduate students, Hawassa Ethiopia
Abstract Background: Use of psychoactive substances (PAS) early in school age implies drug dependence in later life. Although no studies…