Turning Over a New Leaf: Cannabinoid and Endocannabinoid Modulation of Immune Function
Abstract Cannabis is a complex substance that harbors terpenoid-like compounds referred to as phytocannabinoids. The major psychoactive phytocannabinoid found in…
Free
A quantitative epigenetic approach for the assessment of cigarette consumption
Abstract Smoking is the largest preventable cause of morbidity and mortality in the world. Despite the development of numerous preventive…
Primary Macrophage Chemotaxis Induced by Cannabinoid Receptor 2 Agonists Occurs Independently of the CB2 Receptor
Abstract Activation of CB2 has been demonstrated to induce directed immune cell migration. However, the ability of CB2 to act…
Developing the Moti-4 intervention, assessing its feasibility and pilot testing its effectiveness
Abstract Background: The Moti-4 intervention was developed to prevent addiction and other health problems among vulnerable adolescent cannabis users. The…
Views of General Practitioners on Indoor Environmental Health Risks in the Perinatal Period
Abstract Background: Home is generally perceived as a safety place, whereas the concentration of pollutants, influenced not only by external…
4′-O-methylhonokiol increases levels of 2-arachidonoyl glycerol in mouse brain via selective inhibition of its COX-2-mediated oxygenation
Abstract Background and purpose: 4′-O-methylhonokiol (MH) is a natural product showing anti-inflammatory, anti-osteoclastogenic, and neuroprotective effects. MH was reported to…
Comparing treatment effects of oral THC on simulated and on-the-road driving performance: testing the validity of driving simulator drug research
Abstract Rationale: The driving simulator provides a safe and controlled environment for testing driving behaviour efficiently. The question is whether…
Acute fatal posthypoxic leukoencephalopathy following benzodiazepine overdose: a case report and review of the literature
Abstract Background: Among the rare neurological complications of substances of abuse is the selective cerebral white matter injury (leukoencephalopathy). Of…
Narrative review of the safety and efficacy of marijuana for the treatment of commonly state-approved medical and psychiatric disorders
Abstract The present investigation aimed to provide an objective narrative review of the existing literature pertaining to the benefits and…
Sex-Dependent Vulnerability to Cannabis Abuse in Adolescence
Abstract The goal of this review is to summarize current evidence for sex differences in the response to cannabinoid compounds,…